CVE-2025-12921

Dec. 2, 2025, 4:12 p.m.

5.3
Medium

Description

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

Product(s) Impacted

Vendor Product Versions
Openclinica
  • Openclinica
  • 3.12.2, 3.13

Weaknesses

Common security weaknesses mapped to this vulnerability.

CWE-74
Improper Neutralization of Special Elements in Output Used by a Downstream Component ('Injection')
The product constructs all or part of a command, data structure, or record using externally-influenced input from an upstream component, but it does not neutralize or incorrectly neutralizes special elements that could modify how it is parsed or interpreted when it is sent to a downstream component.
CWE-91
XML Injection (aka Blind XPath Injection)
The product does not properly neutralize special elements that are used in XML, allowing attackers to modify the syntax, content, or commands of the XML before it is processed by an end system.

*CPE(s)

Affected systems and software identified for this CVE.

Type Vendor Product Version Update Edition Language Software Edition Target Software Target Hardware Other Information
a openclinica openclinica 3.12.2 / / / community / / /
a openclinica openclinica 3.13 / / / community / / /

References

https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md
https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc
https://vuldb.com/?ctiid.331641
https://vuldb.com/?id.331641
https://vuldb.com/?submit.680872
https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md
https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc

Tags

CWE-91
CWE-74
cna@vuldb.com
2025-11-10
CVE-2025-12921

CVSS Score

5.3 / 10

CVSS Data - 4.0

  • Attack Vector: NETWORK
  • Attack Complexity: LOW
  • Attack Requirements: NONE
  • Privileges Required: LOW
  • User Interaction: NONE
  • Scope:
  • Confidentiality Impact: LOW
  • Integrity Impact: NONE
  • Availability Impact: NONE
  • Exploit Maturity: PROOF_OF_CONCEPT

    • CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X

    View Vector String

Timeline

Published: Nov. 10, 2025, 12:15 a.m.
Last Modified: Dec. 2, 2025, 4:12 p.m.

Status : Analyzed

CVE has had analysis completed and all data associations made.

More info

Source

cna@vuldb.com

*Disclaimer: Some vulnerabilities do not have an associated CPE. To enhance the data, we use AI to infer CPEs based on CVE details. This is an automated process and might not always be accurate.